CYSTEAMINE HYDROCHLORIDE for synthesis

Lab Chemical-60

CYSTEAMINE HYDROCHLORIDE for synthesis

Part No. RXSOL-60-6604-395

CYSTEAMINE HYDROCHLORIDE for synthesis

Key details

Part number RXSOL-60-6604-395
Standard packing 0.00 Box
Supply locations [CYSTEAMINE HYDROCHLORIDE for synthesis] manufacturers, suppliers, exporters in Mumbai, Gandhidham, Kolkata, Varanasi, Visakhapatnam, Chennai, Fujairah, Dubai, Canada BC, Barka, Sohar, Muscat, Oman. Lab chemicals manufacturers, suppliers, exporters in India, UAE Middle East, Barka, Sohar, Muscat, Oman, Canada. [CYSTEAMINE HYDROCHLORIDE for synthesis] is available in small packing as well as in bulk. Buy premium quality [CYSTEAMINE HYDROCHLORIDE for synthesis] and other lab chemicals from one of the most trusted brands.

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Application

<p style="text-align: justify;">
<span style="font-size:14px;"><strong>Cysteamine is a cystine depleting agent used to treat the effects of cystinosis. Cystinosis is a rare disease caused by mutations in the CTNS gene that encodes for cystinosin, a protein responsible for transporting cystine out of the cell lysosome.</strong></span></p>

Using Procedure

<div style="text-align: justify;">
<span style="font-size:14px;"><strong>110 lbs or more:</strong></span></div>
<div style="text-align: justify;">
<span style="font-size:14px;"><strong>-Initial dose: 0.3 to 0.5 g/day orally divided in 4 doses. Increase dose gradually over 4 to 6 weeks if the WBC cystine level remains above 2 nmol half-cystine/mg protein.</strong></span></div>
<div style="text-align: justify;">
<span style="font-size:14px;"><strong>-Maintenance dose: 2 g/day orally divided in 4 doses</strong></span></div>
<div style="text-align: justify;">
 </div>
<div style="text-align: justify;">
<span style="font-size:14px;"><strong>Delayed-release capsule:</strong></span></div>
<div style="text-align: justify;">
<span style="font-size:14px;"><strong>-Initial dose: 0.2 to 0.3 g/m2/day orally divided in 2 doses, every 12 hours. Increase dose gradually over 4 to 6 weeks if the WBC cystine level remains above 1 nmol half-cystine/mg protein.</strong></span></div>
<div style="text-align: justify;">
<span style="font-size:14px;"><strong>-Maintenance dose: 1.3 g/m2/day orally divided in 2 doses, every 12 hours</strong></span></div>
<div style="text-align: justify;">
<span style="font-size:14px;"><strong>Maximum dose: 1.95 g/m2/day</strong></span></div>
<div id="cke_pastebin" style="position: absolute; left: -1000px; top: 12px; width: 1px; height: 1px; overflow: hidden;">
-Maximum dose: 1.95 g/m2/day110 lbs or more:</div>
<div id="cke_pastebin" style="position: absolute; left: -1000px; top: 12px; width: 1px; height: 1px; overflow: hidden;">
-Initial dose: 0.3 to 0.5 g/day orally divided in 4 doses. Increase dose gradually over 4 to 6 weeks if the WBC cystine level remains above 2 nmol half-cystine/mg protein.</div>
<div id="cke_pastebin" style="position: absolute; left: -1000px; top: 12px; width: 1px; height: 1px; overflow: hidden;">
-Maintenance dose: 2 g/day orally divided in 4 doses</div>
<div id="cke_pastebin" style="position: absolute; left: -1000px; top: 12px; width: 1px; height: 1px; overflow: hidden;">
 </div>
<div id="cke_pastebin" style="position: absolute; left: -1000px; top: 12px; width: 1px; height: 1px; overflow: hidden;">
Delayed-release capsule:</div>
<div id="cke_pastebin" style="position: absolute; left: -1000px; top: 12px; width: 1px; height: 1px; overflow: hidden;">
-Initial dose: 0.2 to 0.3 g/m2/day orally divided in 2 doses, every 12 hours. Increase dose gradually over 4 to 6 weeks if the WBC cystine level remains above 1 nmol half-cystine/mg protein.</div>
<div id="cke_pastebin" style="position: absolute; left: -1000px; top: 12px; width: 1px; height: 1px; overflow: hidden;">
-Maintenance dose: 1.3 g/m2/day orally divided in 2 doses, every 12 hours</div>
<div id="cke_pastebin" style="position: absolute; left: -1000px; top: 12px; width: 1px; height: 1px; overflow: hidden;">
-Maximum dose: 1.95 g/m2/day</div>

Note

<p style="text-align: justify;">
<span style="font-size:14px;"><strong>Cysteamine, as a part of CoA plays a crucial role in metabolism by facilitating thioester formation. However, as a free entity, cysteamine is largely absent from metabolism. By contrast, supraphysiological amounts of this simple aminothiol have profound and selective effects of physiology and certain diseases. </strong></span></p>

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