THIOFLAVINE T
Part No. RXSOL-60-6605-711
THIOFLAVINE T
Key Technical Details
| Part number | RXSOL-60-6605-711 |
|---|---|
| Standard packing | 25.00 Kg.PWD |
| Supply locations | [THIOFLAVINE T] manufacturers, suppliers, exporters in Mumbai, Gandhidham, Kolkata, Varanasi, Visakhapatnam, Chennai, Fujairah, Dubai, Canada BC, Barka, Sohar, Muscat, Oman. Lab chemicals manufacturers, suppliers, exporters in India, UAE Middle East, Barka, Sohar, Muscat, Oman, Canada. [THIOFLAVINE T] is available in small packing as well as in bulk. Buy premium quality [THIOFLAVINE T] and other lab chemicals from one of the most trusted brands. |
<p style="text-align: justify;">
<span style="font-size:14px;"><strong>Thioflavin T (ThT) is a fluorescence dye that has first been used for staining amyloid fibrils in histological samples by Vassar and Culling in 1959 (Vassar and Culling, 1959), its application for detecting and quantifying amyloid fibrils in vitro has first been described by Naiki et al.</strong></span></p>
<p style="text-align: justify;">
<span style="font-size:14px;"><strong>Formation of amyloid fibrils underlies a wide range of human disorders, including Alzheimer's and prion diseases. The amyloid fibrils can be readily detected thanks to thioflavin T (ThT), a small molecule that gives strong fluorescence upon binding to amyloids. Using the amyloid fibrils of Aβ40 and Aβ42 involved in Alzheimer's disease, and of yeast prion protein Ure2, here we study three aspects of ThT binding to amyloids: quantification of amyloid fibrils using ThT, the optimal ThT concentration for monitoring amyloid formation and the effect of ThT on aggregation kinetics.</strong></span></p>
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